🧬 Mutations

Mutations are the run modifiers that shape a Puzzlehouse run, grouped below by archetype — what kind of run each one makes. Every one changes how the run plays — hearts, difficulty, the puzzles you face — never just the score. Rarer cards are stronger, and none is a free win. 🧬 16 mutations

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Risk Swingier runs — more upside, less margin.

Insight Know more, or last longer.

Grade Flatten the climb — every puzzle a band easier.